Effect of Efonidipine on TGF-β1-Induced Cardiac Fibrosis Through Smad2-Dependent Pathway in Rat Cardiac Fibroblasts

Abstract.: Transforming growth factor beta-1 (TGF-β1) plays a critical role in progression of cardiac fibrosis, which may involve intracellular calcium change. We examined effects of efonidipine, a dual T-type and L-type calcium channel blocker (CCB), on TGF-β1-induced fibrotic changes in neonatal r...

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Main Authors: Bai Lei (Author), Hirofumi Hitomi (Author), Tatsuhiko Mori (Author), Yukiko Nagai (Author), Kazushi Deguchi (Author), Hirohito Mori (Author), Tsutomu Masaki (Author), Daisuke Nakano (Author), Hiroyuki Kobori (Author), Yasushi Kitaura (Author), Akira Nishiyama (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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Call Number: A1234.567
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