Topical Sustained-Release Dexamethasone-Loaded Chitosan Nanoparticles: Assessment of Drug Delivery Efficiency in a Rabbit Model of Endotoxin-Induced Uveitis

• Main Authors: Musaed Alkholief (Author), Mohd Abul Kalam (Author), Mohammad Raish (Author), Mushtaq Ahmad Ansari (Author), Nasser B. Alsaleh (Author), Aliyah Almomen (Author), Raisuddin Ali (Author), Aws Alshamsan (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Uveitis is an ocular illness that if not treated properly can lead to a total loss of vision. In this study, we evaluated the utility of HA-coated Dexamethasone-sodium-phosphate (DEX)-chitosan nanoparticles (CSNPs) coated with hyaluronic acid (HA) as a sustained ocular delivery vehicle for the treat...