Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells

• Main Authors: Jiadi Luo (Author), Xiaojing An (Author), Yong Yao (Author), Carla Erb (Author), Annabel Ferguson (Author), Jay K. Kolls (Author), Songqing Fan (Author), Kong Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epithelial cells are known to have barrier functions in multiple organs and regulate innate immune responses. Airway epithelial cells respond to IL-17 by altering their transcriptional profiles and producing antimicrobial proteins and neutrophil chemoattractants. Although IL-17 has been shown to pro...