Anti-Bronchospasmodic Effect of JME-173, a Novel Mexiletine Analog Endowed With Highly Attenuated Anesthetic Activity

Local anesthetics (LAs), such as lidocaine and mexiletine, inhibit bronchoconstriction in asthmatics, but adverse effects limit their use for this specific clinical application. In this study, we describe the anti-spasmodic properties of the mexiletine analog 2-(2-aminopropoxy)-3,5-dimethyl, 4-Br-be...

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Main Authors: Katharinne Ingrid Moraes Carvalho (Author), Diego de Sá Coutinho (Author), Humberto Cavalcante Joca (Author), Artur Santos Miranda (Author), Jader dos Santos Cruz (Author), Emerson Teixeira Silva (Author), Marcus Vinícius Nora Souza (Author), Robson Xavier Faria (Author), Patricia Machado Rodrigues e Silva (Author), Jorge Carlos Santos Costa (Author), Marco Aurélio Martins (Author)
Format: Book
Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
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3rd Floor Main Library

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