The Proresolving Lipid Mediator Maresin1 Alleviates Experimental Pancreatitis via Switching Macrophage Polarization

• Main Authors: Yingying Lu (Author), Guotao Lu (Author), Lin Gao (Author), Qingtian Zhu (Author), Jing Xue (Author), Jingzhu Zhang (Author), Xiaojie Ma (Author), Nan Ma (Author), Qi Yang (Author), Jie Dong (Author), Weijuan Gong (Author), Weiqin Li (Author), Zhihui Tong (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose. Previous studies showed that Maresin1 (MaR1), one of the metabolites from docosahexaenoic acid (DHA), could alleviate acute inflammation and prompt inflammation resolution. Also, it attenuated pancreatic injury in caerulein-induced acute pancreatitis (AP) in mice. However, th...