The Human Amnion Epithelial Cell Secretome Decreases Hepatic Fibrosis in Mice with Chronic Liver Fibrosis

• Main Authors: Majid Alhomrani (Author), Jeanne Correia (Author), Marcus Zavou (Author), Bryan Leaw (Author), Nathan Kuk (Author), Rong Xu (Author), Mohamed I. Saad (Author), Alexander Hodge (Author), David W. Greening (Author), Rebecca Lim (Author), William Sievert (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hepatic stellate cells (HSCs) are the primary collagen-secreting cells in the liver. While HSCs are the major cell type involved in the pathogenesis of liver fibrosis, hepatic macrophages also play an important role in mediating fibrogenesis and fibrosis resolution. Previously, we observ...