Intradermal delivery of receptor‐binding domain of SARS‐CoV‐2 spike protein with dissolvable microneedles to induce humoral and cellular responses in mice

• Main Authors: Chaiyaporn Kuwentrai (Author), Jinming Yu (Author), Li Rong (Author), Bao‐Zhong Zhang (Author), Ye‐Fan Hu (Author), Hua‐Rui Gong (Author), Ying Dou (Author), Jian Deng (Author), Jian‐Dong Huang (Author), Chenjie Xu (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The S1 subunit of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike protein contains an immunogenic receptor‐binding domain (RBD), which is a promising candidate for the development of a potential vaccine. This study demonstrated that intradermal delivery of an S‐RBD vaccin...