Baseline and acquired resistance to bedaquiline, linezolid and pretomanid, and impact on treatment outcomes in four tuberculosis clinical trials containing pretomanid.

• Main Authors: Juliano Timm (Author), Anna Bateson (Author), Priya Solanki (Author), Ana Paleckyte (Author), Adam A Witney (Author), Sylvia A D Rofael (Author), Stella Fabiane (Author), Morounfolu Olugbosi (Author), Timothy D McHugh (Author), Eugene Sun (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bedaquiline (B), pretomanid (Pa) and linezolid (L) are key components of new regimens for treating rifampicin-resistant tuberculosis (TB). However, there is limited information on the global prevalence of resistance to these drugs and the impact of resistance on treatment outcomes. Mycobacterium tub...