Baseline and acquired resistance to bedaquiline, linezolid and pretomanid, and impact on treatment outcomes in four tuberculosis clinical trials containing pretomanid.

• Hoofdauteurs: Juliano Timm (Auteur), Anna Bateson (Auteur), Priya Solanki (Auteur), Ana Paleckyte (Auteur), Adam A Witney (Auteur), Sylvia A D Rofael (Auteur), Stella Fabiane (Auteur), Morounfolu Olugbosi (Auteur), Timothy D McHugh (Auteur), Eugene Sun (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2023-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Bedaquiline (B), pretomanid (Pa) and linezolid (L) are key components of new regimens for treating rifampicin-resistant tuberculosis (TB). However, there is limited information on the global prevalence of resistance to these drugs and the impact of resistance on treatment outcomes. Mycobacterium tub...