Monomethyl lithospermate alleviates ischemic stroke injury in middle cerebral artery occlusion mice in vivo and protects oxygen glucose deprivation/reoxygenation induced SHSY-5Y cells in vitro via activation of PI3K/Akt signaling

• Main Authors: Fang Yang (Author), Ze-Ran Chen (Author), Xu-Hong Yang (Author), Yue Xu (Author), Ning-Jing Ran (Author), Mei-Jun Liu (Author), Shuo-Guo Jin (Author), Hua-Nan Jia (Author), Yang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stroke is a fatal neurological disease, which seriously threatens human health and life. Ischemic stroke (IS) is the most common type of stroke in clinic. Its pathogenesis is very complex, mainly caused by nerve damage caused by brain blood supply disorder. Previous studies have confirmed that natur...