[¹⁸F]2-Fluoro-2-deoxy-sorbitol PET Imaging for Quantitative Monitoring of Enhanced Blood-Brain Barrier Permeability Induced by Focused Ultrasound

• Main Authors: Gaëlle Hugon (Author), Sébastien Goutal (Author), Ambre Dauba (Author), Louise Breuil (Author), Benoit Larrat (Author), Alexandra Winkeler (Author), Anthony Novell (Author), Nicolas Tournier (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Focused ultrasound in combination with microbubbles (FUS) provides an effective means to locally enhance the delivery of therapeutics to the brain. Translational and quantitative imaging techniques are needed to noninvasively monitor and optimize the impact of FUS on blood-brain barrier (BBB) permea...