Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer

• Main Authors: Ai-Ho Liao (Author), Yu-An Lee (Author), Dao-Lung Lin (Author), Ho-Chiao Chuang (Author), Jehng-Kang Wang (Author), Ching-En Chang (Author), Hsiang-Tzu Li (Author), Ting-Yi Wu (Author), Cheng-Ping Shih (Author), Chih-Hung Wang (Author), Yueng-Hsiang Chu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractOver the past 50 years, 5-fluorouracil (5-FU) has played a critical role in the systemic chemotherapy of cancer patients. Bolus intravenous (IV) 5-FU infusion has been used due to the limitation of its extremely short half-life (10-15 min). This study used ultrasound (US) mediating 5-FU-load...