Na⁺/K⁺-ATPase Alpha 2 Isoform Elicits Rac1-Dependent Oxidative Stress and TLR4-Induced Inflammation in the Hypothalamic Paraventricular Nucleus in High Salt-Induced Hypertension

• Main Authors: Qing Su (Author), Xiao-Jing Yu (Author), Xiao-Min Wang (Author), Bo Peng (Author), Juan Bai (Author), Hong-Bao Li (Author), Ying Li (Author), Wen-Jie Xia (Author), Li-Yan Fu (Author), Kai-Li Liu (Author), Jin-Jun Liu (Author), Yu-Ming Kang (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Numerous studies have indicated that a high salt diet inhibits brain Na⁺/K⁺-ATPase (NKA) activity, and affects oxidative stress and inflammation in the paraventricular nucleus (PVN). Furthermore, Na⁺/K<sup>+</s...