Histaminergic transmission slows progression of amyotrophic lateral sclerosis

• Main Authors: Savina Apolloni (Author), Susanna Amadio (Author), Paola Fabbrizio (Author), Giovanna Morello (Author), Antonio Gianmaria Spampinato (Author), Emanuele Claudio Latagliata (Author), Illari Salvatori (Author), Daisy Proietti (Author), Alberto Ferri (Author), Luca Madaro (Author), Stefano Puglisi‐Allegra (Author), Sebastiano Cavallaro (Author), Cinzia Volonté (Author)
• Format: Book
• Published: Wiley, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti‐inflammatory features in amyotrophic lateral sclerosis (ALS) microglia. Drugs potentiating the endogenous release of histamine are in trial for n...