Establishment of a population pharmacokinetics model of vancomycin in 94 infants with septicemia and its application in individualized therapy

• Main Authors: Zhiling Li (Author), Hongjing Li (Author), Chenyu Wang (Author), Zheng Jiao (Author), Feng Xu (Author), Huajun Sun (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We aim to develop a population pharmacokinetics (PopPK) model of vancomycin for the treatment of septicemia in infants younger than one year. Factors influence of the PK was investigated to optimize vancomycin dosing regimen. Methods The nonlinear mixed effects modelling software...