Sustained-Release and pH-Adjusted Alginate Microspheres-Encapsulated Doxorubicin Inhibit the Viabilities in Hepatocellular Carcinoma-Derived Cells

• Main Authors: Cheng-Tang Pan (Author), Ruei-Siang Yu (Author), Chih-Jung Yang (Author), Lih-Ren Chen (Author), Zhi-Hong Wen (Author), Nai-Yu Chen (Author), Hsin-You Ou (Author), Chun-Yen Yu (Author), Yow-Ling Shiue (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of this study aimed to develop biodegradable calcium alginate microspheres carrying doxorubicin (Dox) at the micrometer-scale for sustained release and the capacity of pH regulatory for transarterial chemoembolization. Ultrasonic atomization and CaCl₂ cross-linki...