FKBP Ligands-Where We Are and Where to Go?

• Autori principali: Jürgen M. Kolos (Autore), Andreas M. Voll (Autore), Michael Bauder (Autore), Felix Hausch (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

In recent years, many members of the FK506-binding protein (FKBP) family were increasingly linked to various diseases. The binding domain of FKBPs differs only in a few amino acid residues, but their biological roles are versatile. High-affinity ligands with selectivity between close homologs are sc...