Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer's Disease

• मुख्य लेखकों: Ignazio Schino (लेखक), Mariangela Cantore (लेखक), Modesto de Candia (लेखक), Cosimo D. Altomare (लेखक), Catarina Maria (लेखक), João Barros (लेखक), Vasco Cachatra (लेखक), Patrícia Calado (लेखक), Karina Shimizu (लेखक), Adilson A. Freitas (लेखक), Maria C. Oliveira (लेखक), Maria J. Ferreira (लेखक), José N. C. Lopes (लेखक), Nicola A. Colabufo (लेखक), Amélia P. Rauter (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Alzheimer's Disease (AD) is characterized by a progressive cholinergic neurotransmission imbalance, with a decrease of acetylcholinesterase (AChE) activity followed by a significant increase of butyrylcholinesterase (BChE) in the later AD stages. BChE activity is also crucial for the developmen...