Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

• Main Authors: João Calmeiro (Author), Mylène A. Carrascal (Author), Adriana Ramos Tavares (Author), Daniel Alexandre Ferreira (Author), Célia Gomes (Author), Amílcar Falcão (Author), Maria Teresa Cruz (Author), Bruno Miguel Neves (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Throughout the last decades, dendritic cell (DC)-based anti-tumor vaccines have proven to be a safe therapeutic approach, although with inconsistent clinical results. The functional limitations of ex vivo monocyte-derived dendritic cells (MoDCs) commonly used in these therapies are one of the pointe...