Potential role of endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity-an update

• Main Authors: Mingli Sun (Author), Xin Zhang (Author), Boxuan Tan (Author), Qingya Zhang (Author), Xiaopeng Zhao (Author), Dan Dong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a chemotherapy agent, doxorubicin is used to combat cancer. However, cardiotoxicity has limited its use. The existing strategies fail to eliminate doxorubicin-induced cardiotoxicity, and an in-depth exploration of its pathogenesis is in urgent need to address the issue. Endoplasmic reticulum stre...