Cover Image

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression

Abstract Background Antrodia cinnamomea is an indigenous medicinal mushroom in Taiwan, commonly used for the treatment of cancers and inflammatory disorders. 4-acetylantroquinonol B (4AAQB) is one of the active component isolated from the mycelium of A. cinnamomea. However, whether 4AAQB exhibits an...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chien-Hsin Chang (Author), Chun-Chieh Hsu (Author), An-Sheng Lee (Author), Shih-Wei Wang (Author), Kung-Tin Lin (Author), Wei-Luen Chang (Author), Hui-Chin Peng (Author), Wen-Chiung Huang (Author), Ching-Hu Chung (Author)
Format:	Book
Published:	BMC, 2018-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
by: Xia Huang, et al.
Published: (2017)

Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation
by: Shuai Guo, et al.
Published: (2018)

HMGB1 Acts in Synergy with Lipopolysaccharide in Activating Rheumatoid Synovial Fibroblasts via p38 MAPK and NF-κB Signaling Pathways
by: Zheng-Wen He, et al.
Published: (2013)

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways
by: Shuang Peng, et al.
Published: (2016)

Neurotropin inhibits neuroinflammation via suppressing NF-κB and MAPKs signaling pathways in lipopolysaccharide-stimulated BV2 cells
by: Yuqiu Zheng, et al.
Published: (2018)

Magnoliae flos Downregulated Lipopolysaccharide-Induced Inflammatory Responses via NF-κB/ERK-JNK MAPK/STAT3 Pathways
by: Tae-Young Gil, et al.
Published: (2022)

Rosmarinic Acid Attenuates the Lipopolysaccharide-Provoked Inflammatory Response of Vascular Smooth Muscle Cell via Inhibition of MAPK/NF-κB Cascade
by: Ching-Pei Chen, et al.
Published: (2022)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
by: Wei Wang, et al.
Published: (2020)

Eucalyptus essential oils inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through reducing MAPK and NF-κB pathways
by: Chen-Lung Ho, et al.
Published: (2020)

Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways
by: Mi Zhou, et al.
Published: (2024)

Triptriolide Alleviates Lipopolysaccharide-Induced Liver Injury by Nrf2 and NF-κB Signaling Pathways
by: Yi-Qi Yang, et al.
Published: (2018)

Remifentanil Protects against Lipopolysaccharide-Induced Inflammation through PARP-1/NF-κB Signaling Pathway
by: Jian-ning Zhang, et al.
Published: (2019)

Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on <sup>∙</sup>OH Radicals and HO-1 Expression
by: Thanasekaran Jayakumar, et al.
Published: (2021)

Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
by: Chi-Han Huang, et al.
Published: (2021)

FJU‐C28 inhibits the endotoxin‐induced pro‐inflammatory cytokines expression via suppressing JNK, p38 MAPK and NF‐κB signaling pathways
by: Fang Jung, et al.
Published: (2021)

Dusuqing granules (DSQ) suppress inflammation in Klebsiella pneumonia rat via NF-κB/MAPK signaling
by: Xue Mei, et al.
Published: (2017)

Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages
by: Zhikun Li, et al.
Published: (2019)

DMSO Alleviates LPS-Induced Inflammatory Responses in RAW264.7 Macrophages by Inhibiting NF-κB and MAPK Activation
by: Hyunju Han, et al.
Published: (2023)

Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK, NF-κB, AP-1, and Akt Pathways
by: Yao-Xin Gao, et al.
Published: (2018)

Papaver nudicaule (Iceland poppy) alleviates lipopolysaccharide-induced inflammation through inactivating NF-κB and STAT3
by: Jae-Hyeon Oh, et al.
Published: (2019)

Baicalin Alleviates Lipopolysaccharide-Induced Liver Inflammation in Chicken by Suppressing TLR4-Mediated NF-κB Pathway
by: Ping Cheng, et al.
Published: (2017)

Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways
by: Xin Zhi, et al.
Published: (2020)

Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF-κB activity
by: Wei Deng, et al.
Published: (2022)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
by: Minjun Yao, et al.
Published: (2022)

Acacetin inhibits inflammation by blocking MAPK/NF-κB pathways and NLRP3 inflammasome activation
by: Juan Bu, et al.
Published: (2024)

<i>Artemisia gmelinii</i> Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway
by: Seung Yong Kim, et al.
Published: (2022)

Caffeine regulates both osteoclast and osteoblast differentiation via the AKT, NF-κB, and MAPK pathways
by: Yue Miao, et al.
Published: (2024)

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation
by: Yuanyuan Zhuang, et al.
Published: (2017)

The mechanism of nicotinamide on reducing acute lung injury by inhibiting MAPK and NF-κB signal pathway
by: Qun Zhang, et al.
Published: (2021)

Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets
by: Wei-Chieh Huang, et al.
Published: (2023)

Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation
by: Jingyu Ni, et al.
Published: (2020)

Anti-Inflammatory Effect of Rhapontici Radix Ethanol Extract via Inhibition of NF-κB and MAPK and Induction of HO-1 in Macrophages
by: Yun Hee Jeong, et al.
Published: (2016)

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway
by: Yong Zhang, et al.
Published: (2021)

Oxymatrine protects against l-arginine-induced acute pancreatitis and intestine injury involving Th1/Th17 cytokines and MAPK/NF-κB signalling
by: Zhiqiang Zhang, et al.
Published: (2019)

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways
by: Xuantao Hu, et al.
Published: (2020)

Anhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways
by: Qing Liu, et al.
Published: (2017)

Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes
by: Feng Zhou, et al.
Published: (2019)

Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway
by: Xin Lv, et al.
Published: (2021)

Recombinant Human Endostatin Suppresses Mouse Osteoclast Formation by Inhibiting the NF-κB and MAPKs Signaling Pathways
by: Non eChen, et al.
Published: (2016)

N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways
by: Li-Jun Huang, et al.
Published: (2022)