Synthesis and preliminary evaluation of brominated 5-methyl-2,4-dihydropyrazol-3-one and its derivatives as cytotoxic agents

• Main Authors: Rahat Khan (Author), Md. Imam Uddin (Author), Md. Sultan Alam (Author), Mohammad Mamun Hossain (Author), Md. Rabiul Islam (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2008-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Derivatives of 5-methyl-2,4-dihydro-pyrazol-3-one (1a), 5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one (1b) and 2-(2,4-dinitro-phenyl)-5-methyl-2,4-dihydro-pyrazol-3-one (1c) have been brominated in various ways. The compounds (1a, 1b, 1c) were synthesized by condensation reaction between the ethylacet...