Expanding the Antimalarial Drug Arsenal-Now, But How?

• Huvudskapare: Rajeev K. Mehlotra (Författare, medförfattare), Brian T. Grimberg (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: MDPI AG, 2011-04-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

The number of available and effective antimalarial drugs is quickly dwindling. This is mainly because a number of drug resistance-associated mutations in malaria parasite genes, such as crt, mdr1, dhfr/dhps, and others, have led to widespread resistance to all known classes of antimalarial compounds...