Expanding the Antimalarial Drug Arsenal-Now, But How?

• Main Authors: Rajeev K. Mehlotra (Author), Brian T. Grimberg (Author)
• Formato: Libro
• Publicado: MDPI AG, 2011-04-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The number of available and effective antimalarial drugs is quickly dwindling. This is mainly because a number of drug resistance-associated mutations in malaria parasite genes, such as crt, mdr1, dhfr/dhps, and others, have led to widespread resistance to all known classes of antimalarial compounds...