Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations

• Main Authors: Amir Krivoy (Author), Eromona Whiskey (Author), Henrietta Webb-Wilson (Author), Dan Joyce (Author), Derek K. Tracy (Author), Fiona Gaughran (Author), James H. MacCabe (Author), Sukhwinder S. Shergill (Author)
• Format: Book
• Published: SAGE Publishing, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Clozapine is the only medication licenced for treating patients with treatment-refractory schizophrenia. However, there are no evidence-based guidelines as to the optimal plasma level of clozapine to aim for, and their association with clinical and functional outcome. Objective: We asses...