Digital workflows for pathological assessment of rat estrous cycle stage using images of uterine horn and vaginal tissue

• Main Authors: Shinichi Onishi (Author), Riku Egami (Author), Yuya Nakamura (Author), Yoshinobu Nagashima (Author), Kaori Nishihara (Author), Saori Matsuo (Author), Atsuko Murai (Author), Shuji Hayashi (Author), Yoshifumi Uesumi (Author), Atsuhiko Kato (Author), Hiroyuki Tsunoda (Author), Masaki Yamazaki (Author), Hideaki Mizuno (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Assessment of the estrous cycle of mature female mammals is an important component of verifying the efficacy and safety of drug candidates. The common pathological approach of relying on expert observation has several drawbacks, including laborious work and inter-viewer variability. The recent adven...