Comparison of time and dose dependent gene expression and affected pathways in primary human fibroblasts after exposure to ionizing radiation

• Main Authors: Lara Kim Brackmann (Author), Alicia Poplawski (Author), Caine Lucas Grandt (Author), Heike Schwarz (Author), Thomas Hankeln (Author), Steffen Rapp (Author), Sebastian Zahnreich (Author), Danuta Galetzka (Author), Iris Schmitt (Author), Christian Grad (Author), Lukas Eckhard (Author), Johanna Mirsch (Author), Maria Blettner (Author), Peter Scholz-Kreisel (Author), Moritz Hess (Author), Harald Binder (Author), Heinz Schmidberger (Author), Manuela Marron (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Exposure to ionizing radiation induces complex stress responses in cells, which can lead to adverse health effects such as cancer. Although a variety of studies investigated gene expression and affected pathways in human fibroblasts after exposure to ionizing radiation, the under...