Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice

• मुख्य लेखकों: Yohei Sawa (लेखक), Maki Saito (लेखक), Nanae Ishida (लेखक), Miho Ibi (लेखक), Naoko Matsushita (लेखक), Yoshihiro Morino (लेखक), Eiichi Taira (लेखक), Masamichi Hirose (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Recent studies demonstrated that sodium-glucose co-transporter 1 (SGLT1) is associated with human ischemic cardiomyopathy. However, whether SGLT1 blockade is effective against ischemic cardiomyopathy is still uncertain. We examined the effects of KGA-2727, a selective SGLT1 inhibitor, on myocardial...