Structure-Activity Relationship Studies of Chalcones and Diarylpentanoids with Antitumor Activity: Potency and Selectivity Optimization

• Ngā kaituhi matua: Joana Moreira (Author), Joana B. Loureiro (Author), Danilo Correia (Author), Andreia Palmeira (Author), Madalena M. Pinto (Author), Lucília Saraiva (Author), Honorina Cidade (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2023-09-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

We previously reported that chalcone <b>CM-M345</b> (<b>1</b>) and diarylpentanoid <b>BP-C4</b> (<b>2</b>) induced p53-dependent growth inhibitory activity in human cancer cells. Herein, <b>CM-M345</b> (<b>1</b>) and <b>BP...