Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury

• Principais autores: Nan Li (Autor), Dong Weng (Autor), Shan-Mei Wang (Autor), Yuan Zhang (Autor), Shan-Shan Chen (Autor), Zhao-Fang Yin (Autor), Jiali Zhai (Autor), Judy Scoble (Autor), Charlotte C. Williams (Autor), Tao Chen (Autor), Hui Qiu (Autor), Qin Wu (Autor), Meng-Meng Zhao (Autor), Li-Qin Lu (Autor), Xavier Mulet (Autor), Hui-Ping Li (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The advent of nanomedicine requires novel delivery vehicles to actively target their site of action. Here, we demonstrate the development of lung-targeting drug-loaded liposomes and their efficacy, specificity and safety. Our study focuses on glucocorticoids methylprednisolone (MPS), a commonly used...