Carbon Monoxide-Loaded Red Blood Cell Prevents the Onset of Cisplatin-Induced Acute Kidney Injury

• Main Authors: Taisei Nagasaki (Author), Hitoshi Maeda (Author), Hiroki Yanagisawa (Author), Kento Nishida (Author), Kazuki Kobayashi (Author), Naoki Wada (Author), Isamu Noguchi (Author), Ryotaro Iwakiri (Author), Kazuaki Taguchi (Author), Hiromi Sakai (Author), Junji Saruwatari (Author), Hiroshi Watanabe (Author), Masaki Otagiri (Author), Toru Maruyama (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin-induced acute kidney injury (AKI) is an important factor that limits the clinical use of this drug for the treatment of malignancies. Oxidative stress and inflammation are considered to be the main causes of not only cisplatin-induced death of cancer cells but also cisplatin-induced AKI. T...