Influence of TNF and IL17 Gene Polymorphisms on the Spondyloarthritis Immunopathogenesis, Regardless of HLA-B27, in a Brazilian Population

• Main Authors: Marco A. Rocha Loures (Author), Luciana C. Macedo (Author), Denise M. Reis (Author), Camila F. Oliveira (Author), Jean L. Meneguetti (Author), Gabriela F. Martines (Author), Janisleya S. F. Neves (Author), Eliana de Souza (Author), Ana M. Sell (Author), Jeane E. L. Visentainer (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objectives. Spondyloarthritis (SpA) represents a heterogeneous group of immune-mediated inflammatory diseases that have overlapping clinical features, genetic predisposition, and pathogenic mechanisms. Hence, we investigated, through a case-control study, whether single-nucleotide pol...