Comparison of Piperacillin and Tazobactam Pharmacokinetics in Critically Ill Patients with Trauma or with Burn

• Main Authors: Daniel J. Selig (Author), Kevin S. Akers (Author), Kevin K. Chung (Author), Adrian T. Kress (Author), Jeffrey R. Livezey (Author), Elaine D. Por (Author), Kaitlin A. Pruskowski (Author), Jesse P. DeLuca (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics. However, it is unclear if one mechanism of critical illness alters PK more significantly than another. We developed a population PK model...