Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

• Autori principali: Pil Joung Cho (Autore), Sanjita Paudel (Autore), Doohyun Lee (Autore), Yun Ji Jin (Autore), GeunHyung Jo (Autore), Tae Cheon Jeong (Autore), Sangkyu Lee (Autore), Taeho Lee (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2018-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Osthenol is a prenylated coumarin isolated from the root of Angelica koreana and Angelica dahurica, and is an O-demethylated metabolite of osthole in vivo. Its various pharmacological effects have been reported previously. The metabolic pathway of osthenol was partially confirmed in rat osthole stud...