Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

• Main Authors: Pil Joung Cho (Author), Sanjita Paudel (Author), Doohyun Lee (Author), Yun Ji Jin (Author), GeunHyung Jo (Author), Tae Cheon Jeong (Author), Sangkyu Lee (Author), Taeho Lee (Author)
• Format: Book
• Published: MDPI AG, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osthenol is a prenylated coumarin isolated from the root of Angelica koreana and Angelica dahurica, and is an O-demethylated metabolite of osthole in vivo. Its various pharmacological effects have been reported previously. The metabolic pathway of osthenol was partially confirmed in rat osthole stud...