Poor efficacy of preemptive amoxicillin clavulanate for preventing secondary infection from Bothrops snakebites in the Brazilian Amazon: A randomized controlled clinical trial.

• Main Authors: Jacqueline A G Sachett (Author), Iran Mendonça da Silva (Author), Eliane Campos Alves (Author), Sâmella S Oliveira (Author), Vanderson S Sampaio (Author), Fábio Francesconi do Vale (Author), Gustavo Adolfo Sierra Romero (Author), Marcelo Cordeiro Dos Santos (Author), Hedylamar Oliveira Marques (Author), Mônica Colombini (Author), Ana Maria Moura da Silva (Author), Fan Hui Wen (Author), Marcus V G Lacerda (Author), Wuelton M Monteiro (Author), Luiz C L Ferreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Secondary bacterial infections from snakebites contribute to the high complication rates that can lead to permanent function loss and disabilities. Although common in endemic areas, routine empirical prophylactic use of antibiotics aiming to prevent secondary infection lacks a clearly defined policy...