Muscarinic Receptor Binding of the Novel Radioligand, [3H]Imidafenacin in the Human Bladder and Parotid Gland

• Main Authors: Akira Yoshida (Author), Shiori Kuraoka (Author), Yoshihiko Ito (Author), Takashi Okura (Author), Yoshiharu Deguchi (Author), Atsushi Otsuka (Author), Seiichiro Ozono (Author), Masayuki Takeda (Author), Keisuke Masuyama (Author), Isao Araki (Author), Shizuo Yamada (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: The aim of the current study was to demonstrate highly specific and direct binding activity of tritium ([3H])-labeled imidafenacin for labeling muscarinic receptors in human bladder and parotid gland. Specific binding of [3H]imidafenacin in human tissues was saturable, reversible, and of...