Effects of rs958804 and rs7858836 single‐nucleotide polymorphisms of the ASTN2 gene on pain‐related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy

• Main Authors: Rie Inoue (Author), Daisuke Nishizawa (Author), Junko Hasegawa (Author), Kyoko Nakayama (Author), Ken‐ichi Fukuda (Author), Tatsuya Ichinohe (Author), Tsutomu Mieda (Author), Miki Tsujita (Author), Hideyuki Nakagawa (Author), Akira Kitamura (Author), Hiroyuki Sumikura (Author), Kazutaka Ikeda (Author), Masakazu Hayashida (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Opioids are widely used as effective analgesics, but opioid sensitivity varies widely among individuals. The underlying genetic and nongenetic factors are not fully understood. Based on the results of our previous genome‐wide association study, we investigated the effects of sing...