Gene therapy for cystic fibrosis: Challenges and prospects

• Main Authors: Hongshu Sui (Author), Xinghua Xu (Author), Yanping Su (Author), Zhaoqing Gong (Author), Minhua Yao (Author), Xiaocui Liu (Author), Ting Zhang (Author), Ziyao Jiang (Author), Tianhao Bai (Author), Junzuo Wang (Author), Jingjun Zhang (Author), Changlong Xu (Author), Mingjiu Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is a life-threatening autosomal-recessive disease caused by mutations in a single gene encoding cystic fibrosis transmembrane conductance regulator (CFTR). CF effects multiple organs, and lung disease is the primary cause of mortality. The median age at death from CF is in the e...