Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma

There is a crosstalk between Tumor-associated macrophages (TAM) and tumor-infiltrating T cells in tumor environment. TAM could inhibit the activity of cytotoxic T cells; TAM could also regulate the composition of T cells in tumor immune environment. The combination therapy for TAM and tumor infiltra...

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Main Authors: Wei Zhang (Author), Xi Jiang (Author), Youcheng Zou (Author), Lihua Yuan (Author), Xiaobo Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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