Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ERα to inhibit RANKL signaling

• Главные авторы: Keqi Wang (Автор), Yongyan Chen (Автор), Shuo Gao (Автор), Maosi Wang (Автор), Mengmeng Ge (Автор), Qian Yang (Автор), Mingkai Liao (Автор), Lin Xu (Автор), Junjie Chen (Автор), Zhiping Zeng (Автор), Haifeng Chen (Автор), Xiao-kun Zhang (Автор), Ting Lin (Автор), Hu Zhou (Автор)
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• Опубликовано: Elsevier, 2021-02-01T00:00:00Z.
• Предметы: article
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Although different types of drugs are available for postmenopausal osteoporosis, the limitations of the current therapies including drug resistances and adverse effects require identification of novel anti-osteoporosis agents. Here, we defined that norlichexanthone (NOR), a natural product, is a lig...