Low Magnitude of Compression Enhances Biosynthesis of Mesenchymal Stem Cells towards Nucleus Pulposus Cells via the TRPV4-Dependent Pathway

• Autori principali: Yibo Gan (Autore), Bing Tu (Autore), Pei Li (Autore), Jixing Ye (Autore), Chen Zhao (Autore), Lei Luo (Autore), Chengmin Zhang (Autore), Zetong Zhang (Autore), Linyong Zhu (Autore), Qiang Zhou (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2018-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Mesenchymal stem cell- (MSC-) based therapy is regarded as a promising tissue engineering strategy to achieve nucleus pulposus (NP) regeneration for the treatment of intervertebral disc degeneration (IDD). However, it is still a challenge to promote the biosynthesis of MSC to meet the requirement of...