A high-throughput and multiplex microsphere immunoassay based on non-structural protein 1 can discriminate three flavivirus infections.

• Main Authors: Jasmine Tyson (Author), Wen-Yang Tsai (Author), Jih-Jin Tsai (Author), Ludvig Mässgård (Author), Susan L Stramer (Author), Axel T Lehrer (Author), Vivek R Nerurkar (Author), Wei-Kung Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The explosive spread of Zika virus (ZIKV) and associated complications in flavivirus-endemic regions underscore the need for sensitive and specific serodiagnostic tests to distinguish ZIKV, dengue virus (DENV) and other flavivirus infections. Compared with traditional envelope protein-based assays,...