SCID/NOD mice model for 5-FU induced intestinal mucositis: Safety and effects of probiotics as therapy

• Main Authors: Lawrence Huang (Author), Jen-Shiu Chiang Chiau (Author), Mei-Lien Cheng (Author), Wai-Tao Chan (Author), Chuen-Bin Jiang (Author), Szu-Wen Chang (Author), Chun-Yan Yeung (Author), Hung-Chang Lee (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: For chemotherapy patients, intestinal mucositis is a frequent complication. Previously, we evaluated the beneficial effect of oral probiotics in 5-Fluorouracil (5-FU) induced mucositis in BALB/c mice. Here, we used SCID/NOD mice instead to simulate the immunodeficiency of chemotherapy pa...