HBD3 Induces PD-L1 Expression on Head and Neck Squamous Cell Carcinoma Cell Lines

• Main Authors: Maria Paula Gomez Hernandez (Author), Amber M. Bates (Author), Emily E. Starman (Author), Emily A. Lanzel (Author), Carissa Comnick (Author), Xian Jin Xie (Author), Kim A. Brogden (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human β-defensin 3 (HBD3) is an antimicrobial peptide up-regulated in the oral tissues of individuals with head and neck squamous cell carcinomas (HNSCC) and oral squamous cell carcinomas (SCC) and present in high concentrations in their saliva. In this study, we determined if HBD3 contributes to HN...