Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan

• Main Authors: Yiqiao Gao (Author), Wei Li (Author), Jiaqing Chen (Author), Xu Wang (Author), Yingtong Lv (Author), Yin Huang (Author), Zunjian Zhang (Author), Fengguo Xu (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacometabolomics has been already successfully used in toxicity prediction for one specific adverse effect. However in clinical practice, two or more different toxicities are always accompanied with each other, which puts forward new challenges for pharmacometabolomics. Gastrointestinal toxicity...