Application of 2'-OMethylRNA' Antisense Oligomer to Control Candida albicans EFG1 Virulence Determinant

• Main Authors: Daniela Araújo (Author), Nuno Miguel Azevedo (Author), Ana Barbosa (Author), Carina Almeida (Author), Maria Elisa Rodrigues (Author), Mariana Henriques (Author), Sónia Silva (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antisense oligomers and their analogs have been successfully utilized to silence gene expression for the treatment of many human diseases; however, the control of yeast's virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pa...