Application of 2'-OMethylRNA' Antisense Oligomer to Control Candida albicans EFG1 Virulence Determinant

• Auteurs principaux: Daniela Araújo (Auteur), Nuno Miguel Azevedo (Auteur), Ana Barbosa (Auteur), Carina Almeida (Auteur), Maria Elisa Rodrigues (Auteur), Mariana Henriques (Auteur), Sónia Silva (Auteur)
• Format: Livre
• Publié: Elsevier, 2019-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Antisense oligomers and their analogs have been successfully utilized to silence gene expression for the treatment of many human diseases; however, the control of yeast's virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pa...