Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni.

• Main Authors: Thiago Almeida Pereira (Author), Wing-Kin Syn (Author), Frederico Figueiredo Amâncio (Author), Pedro Henrique Diniz Cunha (Author), Julia Fonseca Morais Caporali (Author), Guilherme Vaz de Melo Trindade (Author), Elisângela Trindade Santos (Author), Márcia Maria Souza (Author), Zilton Araújo Andrade (Author), Rafal P Witek (Author), William Evan Secor (Author), Fausto Edmundo Lima Pereira (Author), José Roberto Lambertucci (Author), Anna Mae Diehl (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated. Osteopontin has been implicated in granuloma...