Antimicrobial Activity of Quasi-Enantiomeric <i>Cinchona</i> Alkaloid Derivatives and Prediction Model Developed by Machine Learning

• Main Authors: Alma Ramić (Author), Mirjana Skočibušić (Author), Renata Odžak (Author), Ana Čipak Gašparović (Author), Lidija Milković (Author), Ana Mikelić (Author), Karlo Sović (Author), Ines Primožič (Author), Tomica Hrenar (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-05-01T00:00:00Z.
• Fag: article
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Bacterial infections that do not respond to current treatments are increasing, thus there is a need for the development of new antibiotics. Series of 20 <i>N</i>-substituted quaternary salts of cinchonidine (CD) and their quasi-enantiomer cinchonine (CN) were prepared and their antimicro...