DNA methylation‐based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'

• Main Authors: Iben Lyskjær (Author), Solange De Noon (Author), Roberto Tirabosco (Author), Ana Maia Rocha (Author), Daniel Lindsay (Author), Fernanda Amary (Author), Hongtao Ye (Author), Daniel Schrimpf (Author), Damian Stichel (Author), Martin Sill (Author), Christian Koelsche (Author), Nischalan Pillay (Author), Andreas Von Deimling (Author), Stephan Beck (Author), Adrienne M Flanagan (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Diagnosing bone and soft tissue neoplasms remains challenging because of the large number of subtypes, many of which lack diagnostic biomarkers. DNA methylation profiles have proven to be a reliable basis for the classification of brain tumours and, following this success, a DNA methylation...