Role of Inositol-1,4,5-Trisphosphate Receptor in the Regulation of Calcium Transients in Neonatal Rat Ventricular Myocytes

• Main Authors: Zheng Zeng (Author), Heping Zhang (Author), Na Lin (Author), Man Kang (Author), Yuanyuan Zheng (Author), Chen Li (Author), Pingxiang Xu (Author), Yongquan Wu (Author), Dali Luo (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study determined the regulatory effect of inositol 1,4,5-trisphosphate receptors (IP3Rs) on the basal Ca2+ transients in cardiomyocytes. In cultured neonatal rat ventricular myocytes (NRVMs) at different densities, we used confocal microscopy to assess the effect of IP3Rs on the endogenous spon...