Phentolamine Significantly Enhances Macrolide Antibiotic Antibacterial Activity against MDR Gram-Negative Bacteria

• Main Authors: Ze-Hua Cui (Author), Hui-Ling He (Author), Zi-Jian Zheng (Author), Zhao-Qi Yuan (Author), Ying Chen (Author), Xin-Yi Huang (Author), Hao Ren (Author), Yu-Feng Zhou (Author), Dong-Hao Zhao (Author), Liang-Xing Fang (Author), Yang Yu (Author), Ya-Hong Liu (Author), Xiao-Ping Liao (Author), Jian Sun (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Multidrug-resistant (MDR) Gram-negative bacterial infections have limited treatment options due to the impermeability of the outer membrane. New therapeutic strategies or agents are urgently needed, and combination therapies using existing antibiotics are a potentially effective means to...