Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma

• Main Authors: Shouyue Zhang (Author), Jin Zhang (Author), Yang An (Author), Xiaoxi Zeng (Author), Ziyi Qin (Author), Yuqian Zhao (Author), Heng Xu (Author), Bo Liu (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autophagy is a critical cellular homeostatic mechanism, and its dysfunction is linked to invasive breast carcinoma (BRCA). Recently, several omics methods have been applied to explore autophagic regulators in BRCA; however, more reliable and robust approaches for identifying crucial regulators and d...